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Chemotherapy-Induced
‍Peripheral Neuropathy

At Nupera, we believe in empowering you with knowledge about Chemotherapy-Induced Peripheral Neuropathy (CIPN). Understanding this condition and its causes is the first step toward discovering natural, effective treatments that promote healing that support healing and improve your quality of life throughout and beyond your cancer journey.
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What is chemo-induced peripheral neuropathy?

Peripheral neuropathy caused by chemotherapy, also known as Chemotherapy-Induced Peripheral Neuropathy (CIPN), is a common side effect of specific cancer treatments. It occurs when chemotherapy drugs damage the peripheral nerves, which are responsible for transmitting signals between the central nervous system (the brain and spinal cord) and the rest of the body. These nerves control various functions, including sensation, movement, and motor coordination.

Signs and symptoms of peripheral neuropathy from chemo

CIPN symptoms can vary widely in severity and type, depending on the extent of nerve damage, the specific chemotherapy drugs used, and the individual's overall health. These symptoms generally fall into three categories: sensory, motor, and autonomic changes.

Sensory Changes

Sensory symptoms are the most common in CIPN and primarily affect the hands and feet, as these are the longest nerves in the body and most susceptible to damage.

  • Numbness or reduced sensation, especially in the hands and feet

  • Tingling or "pins and needles" sensations

  • Burning, stabbing, or shooting pain

  • Increased sensitivity to touch or temperature

Motor Changes

Motor symptoms arise when chemotherapy affects nerves that control muscles, leading to difficulties with movement and coordination.

  • Muscle weakness

  • Difficulty with coordination or balance

  • Trouble with fine motor skills, such as buttoning a shirt

Autonomic Changes (Less Common)

In rare cases, CIPN affects the autonomic nerves, which control involuntary bodily functions.

Early recognition of CIPN symptoms is critical. If you notice any of the above changes, inform your healthcare provider promptly. Timely intervention can help manage symptoms more effectively and prevent them from worsening.

Causes and risk factors of peripheral neuropathy due to chemotherapy

What are the common Causes of Chemotherapy-Induced Peripheral Neuropathy (CIPN)?

Chemotherapy-Induced Peripheral Neuropathy (CIPN) often results from specific cancer treatments that damage nerves. Drugs commonly associated with CIPN include:

  • Platinum-based agents: Cisplatin, Oxaliplatin, Carboplatin
  • Taxanes: Paclitaxel, Docetaxel
  • Vinca alkaloids: Vincristine, Vinblastine
  • Proteasome inhibitors: Bortezomib
  • Others: Thalidomide, Lenalidomide

These drugs can disrupt nerve function by damaging the fibers or the protective myelin sheath, leading to impaired signal transmission.

What are the risk factors of peripheral neuropathy caused by chemo?

Certain factors increase the likelihood of CIPN:

  • High cumulative doses or extended use of chemotherapy drugs
  • Pre-existing nerve damage from conditions like diabetes or alcohol use
  • Older age, which naturally predisposes individuals to nerve sensitivity
  • A prior history of neuropathy or other nerve disorders

How long does CIPN last?

The duration of Chemotherapy-Induced Peripheral Neuropathy (CIPN) varies widely depending on individual factors and the type of chemotherapy used.

  • Temporary Symptoms: For many patients, CIPN symptoms such as tingling, numbness, or pain gradually improve or resolve within a few weeks to months after completing chemotherapy. The nerves begin to heal as the body metabolizes the drugs and recovers.

  • Persistent or Chronic Neuropathy: In some cases, nerve damage may be long-lasting or even permanent. Chronic CIPN can significantly impact the quality of life, leading to ongoing discomfort or mobility challenges. Factors such as the severity of nerve damage, the cumulative dose of chemotherapy, and pre-existing nerve conditions can influence the likelihood of prolonged symptoms.

Management and treatment for chemo-induced peripheral neuropathy

You may have been advised to try the following to keep the pain chemo-induced peripheral neuropathy under control.

  • Medications: Pain relievers, anti-seizure drugs, antidepressants
  • Physical Therapy: To improve strength, balance, and coordination
  • Lifestyle Adjustments: Using assistive devices or modifying activities to reduce strain
  • Natural Remedies: Acupuncture, massage therapy, or dietary supplements

Best Natural Treatment for Chemotherapy-Induced Peripheral Neuropathy (CIPN)

But Nupera’s Innovative 2-Step Treatment is Different.

Most treatments for chemotherapy-induced peripheral neuropathy (CIPN) focus on managing symptoms like pain, tingling, or numbness, providing temporary relief without addressing the root cause of nerve damage. As a result, the condition can persist, affecting quality of life.
Nupera’s innovative 2-step treatment goes beyond symptom management. It targets the underlying nerve damage caused by chemotherapy, promotes healing in the affected nerves, and stimulates regeneration, offering long-lasting relief and improved nerve function.
Find Comfort Today!

Experience lasting relief from peripheral neuropathy with Nupera's innovative 2-step treatment that promotes nerve healing and regeneration.

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